Lead, Urine Test

This urine test monitors exposure to lead or lead chelation therapy. Increased urinary lead excretion indicates excessive lead exposure, regardless of clinical presentation. Chelation therapy monitoring may be indicated.

Lead poisoning through chronic exposure is characterized by:

• Gastrointestinal disturbance
• Anemia
• Insomnia
• Weight loss
• Motor weakness
• Muscle paralysis
• Neuropathy
• Ingestion of large quantities may produce death

Lead and organic lead compounds have numerous commercial and industrial applications, use in paints, plastics, storage batteries, bearing alloys, insecticides, and ceramics. Exposure may also occur through the inhalation of dust containing lead emitted by automobile exhausts. A common source of lead exposure among children is derived through the mouthing of inanimate objects, specifically objects with paint and paint chips that contain lead. Acute lead exposure is rare; however, toxicity may occur through acute ingestion of a lead salt or acetate. Urine is suggested specimen in which chronic lead poisoning may be monitored.