Rheumatoid Arthritis Test - Rheumatoid Factor (RF)

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About Our Rheumatoid Arthritis Test - Rheumatoid Factor (RF)

The Rheumatoid Factor (RF) blood test measures the presence of rheumatoid factor, an autoantibody that can attack healthy tissue when the immune system mistakenly targets the body’s own cells. Elevated RF levels are most commonly associated with rheumatoid arthritis (RA), a chronic autoimmune condition that causes joint inflammation, pain, and progressive damage.

While rheumatoid arthritis is the most well-known condition linked to RF, elevated levels may also appear in other autoimmune or inflammatory disorders. Because RA can begin subtly and worsen over time, early testing plays a critical role in identifying immune system activity before irreversible joint damage occurs.

What Is Included In This Test?

This test measures the concentration of rheumatoid factor in your blood to help assess autoimmune activity.

Your results can help:

Support the diagnosis of rheumatoid arthritis
Identify autoimmune-related inflammation
Assess disease severity and progression risk
Guide follow-up testing such as anti-CCP antibodies or imaging
Assist in early intervention and treatment planning

Although a positive RF result alone does not confirm rheumatoid arthritis, higher levels, especially when symptoms are present, are often linked to more active or aggressive disease.

Who Should Consider This Test?

This test is ideal for individuals experiencing symptoms that may suggest rheumatoid arthritis or autoimmune inflammation.

You should consider this test if you:

Have persistent joint pain, swelling, or stiffness
Experience morning joint stiffness lasting more than 30 minutes
Have unexplained fatigue or low-grade fever
Have a family history of rheumatoid arthritis or autoimmune disease
Want early evaluation to reduce the risk of long-term joint damage

Early detection allows for faster diagnosis, targeted treatment, and improved long-term outcomes.

Convenient, No-Appointment Testing

To complete your test:

Order online through our website
Use the lab locator to find a nearby testing location
Walk in; no appointment required
Access your results securely in your HealthLabs.com account within one to three business days

110% Price Guarantee!

If you find the same test for a lower price from a comparable provider, contact us. We not only match the price, we beat it by an additional 10 percent of the difference.

Common Questions:

How is the Rheumatoid Factor (RF) test different from an ANA test?

The Rheumatoid Factor (RF) test measures a specific autoantibody most commonly associated with rheumatoid arthritis, while the Antinuclear Antibodies (ANA) test detects a broad group of antibodies that target the nuclei of cells.

RF is more focused on autoimmune joint disease, whereas ANA is used as a general screening tool for a wide range of autoimmune and connective tissue disorders, such as lupus and Sjögren’s syndrome. In many cases, both tests are used together to help narrow down the type of autoimmune condition present.

Why is early RF testing important?

Early testing can support faster diagnosis and treatment, helping reduce the risk of irreversible joint damage.

Will anyone see my results besides me?

Your results are stored in your secure online account. They are not shared with anyone else. If you choose, you can print or download them to share with your own doctor.

Do I need to fast before this test?

Fasting is not required for this panel. You can eat and drink normally unless your doctor has given you other instructions.

Can I talk to someone about my results?

Yes. If your results come back abnormal or if you simply have questions, our team is here to support you. You can text our Patient Services team at 1800-579-3914, anytime between 8am and 8pm.

Can I use insurance to pay for this test?

In order to ensure your privacy, we do not bill insurance directly, but you may use HSA or FSA funds. This keeps your results and testing completely private from insurers. We can also provide you with an itemized receipt for insurance reimbursement purposes if you need it.